Details for gene set NCI_IL23-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL23-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.68556225
Normalized Enrichment Score (NES)	-1.5321932
Nominal p-value	0.00952381
FDR q-value	0.22807011
FWER p-Value	0.959

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	STAT5A	2680458	1375	0.523	-0.0443	No
2	IL12RB1	2230338 5420053	1582	0.443	-0.0301	No
3	CYLD	6590079	1812	0.370	-0.0214	No
4	CXCL1	2690537	2144	0.280	-0.0232	No
5	NFKB1	5420358	2177	0.270	-0.0096	No
6	UBE2D3	3190452	2980	0.131	-0.0453	No
7	ARRB2	2060441	3118	0.115	-0.0461	No
8	CHUK	7050736	3349	0.094	-0.0532	No
9	IL1B	2640364	4117	0.049	-0.0917	No
10	CCL2	4760019	4159	0.047	-0.0912	No
11	IL18	6180039	4198	0.046	-0.0907	No
12	JAK2	3780528 6100692 6550577	4243	0.044	-0.0905	No
13	ALOX12B	5340102	4557	0.035	-0.1054	No
14	ITGA3	4570427	4687	0.032	-0.1105	No
15	TNF	6650603	4887	0.028	-0.1197	No
16	BCL3	3990440	5383	0.020	-0.1452	No
17	IL12B	460008	7250	0.008	-0.2453	No
18	PIK3R1	4730671	7437	0.007	-0.2550	No
19	XPO1	540707	7981	0.005	-0.2839	No
20	IL2	1770725	8136	0.005	-0.2919	No
21	IL6	380133	9755	0.000	-0.3792	No
22	RAN	2260446 4590647	9782	0.000	-0.3806	No
23	IFNG	5670592	11695	-0.006	-0.4833	No
24	MALT1	4670292	11831	-0.006	-0.4902	No
25	ATM	3610110 4050524	11982	-0.007	-0.4979	No
26	IL19	6040142	12213	-0.008	-0.5098	No
27	SRC	580132	12478	-0.009	-0.5235	No
28	IL18RAP	3850088	12482	-0.009	-0.5231	No
29	IL24	1500372 7000167	12641	-0.010	-0.5311	No
30	PIK3CA	6220129	12684	-0.010	-0.5327	No
31	IL23R	3990014	12702	-0.011	-0.5331	No
32	IL23A	6290044	12726	-0.011	-0.5337	No
33	FBXW11	6450632	12795	-0.011	-0.5367	No
34	SYK	6940133	12885	-0.012	-0.5409	No
35	REL	360707	13310	-0.015	-0.5629	No
36	BIRC2	2940435 4730020	13581	-0.017	-0.5764	No
37	IL17F	670577	13842	-0.021	-0.5893	No
38	PRKCA	6400551	13942	-0.022	-0.5934	No
39	IL17A	4280369	14067	-0.024	-0.5987	No
40	STAT4	1660373 3130019	14158	-0.025	-0.6021	No
41	ERC1	1580170 2630717 6110762 6840280	14388	-0.030	-0.6127	No
42	NOD2	2510050	14922	-0.048	-0.6387	No
43	CXCL9	1570673	15011	-0.053	-0.6405	No
44	RIPK2	5050072 6290632	15223	-0.066	-0.6481	No
45	IL18R1	270546	15434	-0.083	-0.6547	No
46	IKBKG	3450092 3840377 6590592	15620	-0.102	-0.6588	No
47	SOCS3	5550563	16074	-0.155	-0.6744	Yes
48	IKBKB	6840072	16263	-0.180	-0.6743	Yes
49	TYK2	1660465 1740736	16473	-0.219	-0.6731	Yes
50	MAPK14	5290731	16518	-0.228	-0.6625	Yes
51	TRAF6	4810292 6200132	16620	-0.253	-0.6535	Yes
52	RELB	1400048	17205	-0.414	-0.6613	Yes
53	NFKBIA	1570152	17293	-0.450	-0.6404	Yes
54	NFKB2	2320670	17315	-0.460	-0.6152	Yes
55	RELA	3830075	17328	-0.467	-0.5893	Yes
56	MAP3K14	5890435	17492	-0.536	-0.5675	Yes
57	LCK	3360142	17548	-0.561	-0.5385	Yes
58	BCL10	2360397	17788	-0.705	-0.5112	Yes
59	STAT3	460040 3710341	18021	-0.893	-0.4728	Yes
60	CD4	1090010	18045	-0.930	-0.4210	Yes
61	STAT1	6510204 6590553	18176	-1.089	-0.3659	Yes
62	CD3E	3800056	18269	-1.267	-0.2986	Yes
63	MPO	2360176 2760440 5690176	18346	-1.449	-0.2201	Yes
64	TNFAIP3	2900142	18358	-1.497	-0.1353	Yes
65	TNFRSF1A	1090390 6520735	18550	-2.617	0.0036	Yes